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Updated: Sep 26, 2026

Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice
Published on: October 27, 2014
Acute myocardial infarction and cardiac arrest in a patient receiving paclitaxel
Phong Nguyen-Ho1, Neal S Kleiman, Mario S Verani
1Department of Medicine, Section of Cardiology, Baylor College of Medicine, Houston, USA. phongnguyenho@yahoo.com
Abstract:
A 68-year-old man suffered an acute myocardial infarction while receiving an intravenous infusion of paclitaxel. Coronary angiograms revealed only mild plaquing of the infarct-related artery without significant angiographic obstructions. The authors postulate that paclitaxel may have caused coronary vasospasm and myocardial infarction.
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