Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Apolipoprotein D expression in benign and malignant prostate tissues.

J C Rodríguez1, M Díaz, L O González

  • 1Servicio de Cirugía General Hospital de Jove, Avda. Eduardo Castro s/n 33290 Gijón, Spain.

International Journal of Surgical Investigation
|April 8, 2003
PubMed
Summary

Apolipoprotein D (ApoD) expression in prostate cancer may predict patient survival. ApoD-negative tumors in nonresectable prostate cancer patients indicated shorter survival, suggesting clinical utility.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[In vitro activity of delafloxacin against clinical isolates of carbapenem-resistant Pseudomonas aeruginosa in a stage prior to the clinical use of this drug].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2023
Same author

[Concordance between GeneXpert and Life Real Detection Kit in the diagnosis of acute respiratory infections].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2023
Same author

[Evaluation of the validity of Ag PANBIO-COVID19 in the diagnosis of SARS-CoV-2 infection in asymptomatic or mildly infected patients].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2021
Same author

Impact of Sepsis Flow Chip, a novelty fast microbiology method, in the treatment of bacteremia caused by Gram-negative bacilli.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2021
Same author

Etiology of bloodstream infections at a population level during 2013-2017 in the Autonomous Community of Valencia, Spain.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2020
Same author

Survey of the erythrocyte EPA+DHA levels in the heart attack/stroke belt.

Prostaglandins, leukotrienes, and essential fatty acids·2019

Area of Science:

  • Oncology
  • Biochemistry
  • Molecular Biology

Background:

  • Apolipoprotein D (ApoD) is a protein in human plasma lipid transport.
  • ApoD is regulated by androgens in breast and prostate cancer cell lines.

Purpose of the Study:

  • To examine ApoD expression in normal, benign, and malignant prostate tissues.
  • To investigate the clinical significance of ApoD expression in prostate cancer.

Main Methods:

  • Immunohistochemical assay was used to detect ApoD expression.
  • Prostate tissues (normal, benign hyperplasia, carcinoma) were analyzed.

Main Results:

  • ApoD was detected in normal, benign, and malignant prostate tissues.
  • ApoD expression in carcinomas did not correlate with patient age, tumor stage, grade, or PSA levels.

Related Experiment Videos

  • ApoD-negative immunostaining predicted shorter survival in nonresectable prostate cancer patients (p=0.02).

    • Conclusions:

    • ApoD expression in prostate carcinomas may be clinically useful.
    • ApoD status could help identify prostate lesions with different clinical evolution.