Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antibiotic prophylaxis in urologic prosthetic surgery.

Alex Gomelsky1, Roger R Dmochowski

  • 1Dept of Urologic Surgery, Vanderbilt University School of Medicine, VU Medical Center, Room A1302 Medical Center North, Nashville, TN 37232, USA.

Current Pharmaceutical Design
|April 8, 2003
PubMed
Summary

Preventing infection during urologic prosthetic surgery is crucial. Effective antibiotic prophylaxis, targeting biofilm-forming bacteria like S. epidermidis, is key to avoiding complications and reoperations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Urobiome Analysis in Interstitial Cystitis/Bladder Pain Syndrome Reveals Nuanced Differences Associated with Localized Pain.

International urogynecology journal·2026
Same author

Treatment of refractory idiopathic overactive bladder with incobotulinumtoxinA and vibe delivery system (XAVIER): pilot study.

Minerva urology and nephrology·2026
Same author

Cost-utility of implantable tibial neuromodulation (Revi) versus conservative therapy for urgency urinary incontinence in adults: a US payer perspective.

Journal of medical economics·2026
Same author

Three-Year Efficacy and Safety of Revi Implantable Tibial Neuromodulation from the Pivotal OASIS Study.

The Journal of urology·2026
Same author

Editorial.

Neurourology and urodynamics·2026
Same author

Impact of Revi® Implantable Tibial Neuromodulation on Quality of Life in Patients with Urgency Urinary Incontinence.

International urogynecology journal·2026

Area of Science:

  • Urologic Surgery
  • Biomaterials Science
  • Infectious Disease Prevention

Background:

  • Prosthetic device implantation is common in urologic surgery for conditions like incontinence and erectile dysfunction.
  • Infection and rejection are severe complications, often requiring explantation, long-term antibiotics, and complex reoperation.
  • Dense inflammatory responses can complicate future surgical interventions.

Purpose of the Study:

  • To emphasize the critical need for effective antibiotic prophylaxis in urologic prosthetic surgery.
  • To guide the selection of appropriate antibiotic regimens to prevent prosthetic device infection.
  • To review current understanding of infection prevention strategies and dental procedure prophylaxis.

Main Methods:

  • Review of existing literature on prosthetic device infections and prophylaxis strategies.

Related Experiment Videos

  • Analysis of common pathogens, particularly biofilm-forming bacteria (S. epidermidis, P. aeruginosa).
  • Evaluation of antibiotic efficacy and recommendations for prophylactic regimens.

    • Main Results:

    • Effective antibiotic prophylaxis is essential to prevent bacterial seeding during implantation.
    • Antibiotic regimens must target biofilm-forming bacteria; vancomycin is recommended.
    • Strict sterile technique and pre-operative treatment of reservoirs are vital.
    • Routine dental prophylaxis is generally not warranted for patients with urologic prostheses, except in specific high-risk cases.

    Conclusions:

    • Prophylactic antibiotics are paramount in reducing prosthetic device infections in urology.
    • Targeted antibiotic selection, including vancomycin, is crucial for preventing biofilm formation.
    • While routine dental prophylaxis is not advised, individualized assessment is necessary for immunocompromised or comorbid patients.