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Feeding peptides interact in several ways with the blood-brain barrier
1VA Medical Center and Tulane University School of Medicine, 1601 Perdido Street, New Orleans, LA 70112-1262, USA. akastin@tulane.edu
Current Pharmaceutical Design
|April 8, 2003
Abstract:
The blood-brain barrier (BBB) plays a crucial role in the regulation of body weight and feeding by peptides. This review summarizes the components of the BBB as well as the circumventricular organs (CVOs), the methods used for quantification of the passage of feeding peptides across the BBB, and the various ways by which these peptides can interact with the BBB.