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Pediatric sinovenous thrombosis.

M Cris Johnson1, Nikki Parkerson, Sarah Ward

  • 1Department of Pediatrics, University of Virginia, Charlottesville, Virginia 22908-0386, USA. cj9q@virginia.edu

Journal of Pediatric Hematology/Oncology
|April 8, 2003
PubMed
Summary

Anticoagulation therapy is safe and effective for pediatric sinovenous thrombosis, leading to symptom improvement and no recurrence. This treatment shows promise in managing this condition in children.

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Area of Science:

  • Pediatric Neurology
  • Hematology
  • Vascular Medicine

Background:

  • Pediatric sinovenous thrombosis (PSVT) is a rare but serious condition.
  • Understanding effective treatments and risk factors for PSVT is crucial for improving patient outcomes.

Purpose of the Study:

  • To evaluate the efficacy and safety of anticoagulation for pediatric sinovenous thrombosis.
  • To identify risk factors and clinical presentations associated with PSVT in children.
  • To assess the impact of anticoagulation on clot progression and patient symptoms.

Main Methods:

  • Retrospective chart review of 17 pediatric patients diagnosed with sinovenous thrombosis.
  • Analysis of treatment options, including anticoagulation and surgical intervention.
  • Assessment of clinical outcomes, symptom resolution, and radiologic findings.

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Main Results:

  • Fifteen of 17 patients received anticoagulation therapy without bleeding complications.
  • No patient experienced recurrence of sinovenous thrombosis after initiating anticoagulation.
  • All patients showed symptom improvement; 93% had clot resolution or no change in radiologic findings.

Conclusions:

  • Anticoagulation therapy is a safe and effective treatment for pediatric sinovenous thrombosis.
  • The treatment led to significant clinical improvement and radiologic resolution in most pediatric patients.
  • While generally safe, long-term monitoring for potential neurologic sequelae is warranted.