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Practolol peritonitis presenting as a pelvic mass.

B J Trudinger, D H Fitchett

    British Journal of Obstetrics and Gynaecology
    |April 1, 1976
    PubMed
    Summary
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    Practolol can cause sclerosing fibro-peritonitis, a rare condition that may appear months after stopping the drug. This condition can mimic a pelvic mass, presenting a diagnostic challenge for gynecologists.

    Area of Science:

    • Gastroenterology
    • Pharmacology
    • Gynecology

    Background:

    • Practolol is a beta-blocker previously used for cardiovascular conditions.
    • Drug-induced conditions can manifest with diverse and delayed presentations.
    • Sclerosing fibro-peritonitis is a rare but serious intra-abdominal adhesion disorder.

    Observation:

    • A case of sclerosing fibro-peritonitis is presented.
    • The condition occurred in a patient with a history of practolol therapy.
    • Symptoms arose months after discontinuing practolol due to other side effects.

    Findings:

    • Practolol therapy is identified as the cause of sclerosing fibro-peritonitis.
    • The condition can present as a pelvic mass, potentially misleading gynecological diagnosis.

    Related Experiment Videos

  • Delayed onset of symptoms after drug cessation is a key characteristic.
  • Implications:

    • Highlights the importance of considering drug history in unexplained pelvic masses.
    • Underscores the potential for rare, long-term adverse effects of medications.
    • Emphasizes the need for awareness among clinicians regarding practolol-induced complications.