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Intraductal Injection of LPS as a Mouse Model of Mastitis: Signaling Visualized via an NF-κB Reporter Transgenic
Published on: September 4, 2012
Mastitis therapy and pharmacology
Ronald J Erskine1, Sarah Wagner, Fred J DeGraves
1Department of Large Animal Clinical Science, College of Veterinary Medicine, D-202 VMC, Michigan State University, East Lansing, MI 48824, USA. erskine@cvm.msu.edu
Abstract:
Mastitis remains the most frequent cause of antibacterial use on dairy farms and contributes to a substantial portion of total drug and veterinary costs incurred by the dairy industry. Ultimately, the best outcome of mastitis therapy is a positive effect on the amount of marketed milk harvested and long-term survival of the cow. This article describes the strategies of therapy for bovine mastitis, with an emphasis on antibacterial and anti-inflammatory therapy.
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