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[Advances in the chiral resolution of organophosphorus compounds by liquid chromatography]
Ai-ling Zhou1, Xian-yu Lü, Jun-min Huang
1College of Chemistry, Nankai University, Tianjin 300071, China. zhouailing@eyou.com
Se Pu = Chinese Journal of Chromatography
|April 10, 2003
Abstract:
The developments in the chiral resolution of organophosphorus compounds by liquid chromatography in recent years are reviewed. Two different approaches of separation: indirect resolution (chiral derivatization reagent method) and direct resolution (chiral mobile phase additive and chiral stationary phase), focusing on several chiral stationary phases--Pirkle type, cyclodextrin, cellulose, ligand exchange and other chiral stationary phases are presented. The possible mechanism of chiral recognition is discussed. Eighty-five references are involved.