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Updated: Sep 26, 2026

Rapid Isolation of Stage I Oocytes in Zebrafish Devoid of Granulosa Cells
Published on: July 26, 2024
[Oogenesis of Mozambique tilapia. IV. Yolk formation]
D A Chmilevskiĭ1, T O Kameneva
1Biological Research Institute, St. Petersburg State University, and Institute of Cytology RAS, St. Petersburg. ichtyol1943@mail.ru
Abstract:
Yolk globules in developing oocytes of Tilapia mosambique are formed by two processes: 1) biosynthetical activity of oocyte organoides; 2) vitellogenin migration by micropinocytosis and its further transformation. Undoubtedly, yolk globules of endogenic and exogenic origin are fused. The primary yolk globules are spherical, and the secondary ones are lobular. The latter originate by incorporating the former. The fast growth of the late vitellogenic stage oocytes occurs as a result of active migration of primary yolk globules into the central part of the oocyte and as their association with the secondary yolk globules. In vitellogenic oocytes of T. mosambique no yolk vesicles (cortical granules), were found by any existing methods.
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