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Serum procollagen type III peptide levels in normal rhesus monkeys
Charles Cornelius1, Sharon Strong, Carrie Smith
1Department of Physiological Sciences, California Primate Research Center, University of California, Davis, CA 95616.
Abstract:
Serum levels of the amino-terminal peptide of Type III procollagen (P-III-P) were assayed by radioimmunoassay in 48 Rhesus monkeys from 0.7 to 26.4 years of age. Serum P-III-P levels in ten juvenile monkeys (0.7-4.7 yrs.) were significantly higher (84.5 +/- 66.2 ng/ml, p = 0.05) and ranged from 29.6 to 238.0 ng/ml as compared with 38 monkeys over 5 years of age (21.7 - 9.4 ng/ml), which ranged from 8.5 to 55.5 ng/ml. No significant differences in serum P-III-P levels were observed between any age groups over 5 years of age (5-10, 10-15, 15-20, and > 20) or between male and female monkeys within any age category.