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The Secretory Activity of the Rat Thymus in vitro
Tatyana Yu. Stanievskaya1, Vitaly Ya. Arion, Svetlana N. Moskvina
1Institute of Physico-Chemical Medicine, Moscow, Russia.
Some biochemical and biological characteristics of supernatant from rat thymic stromal cell culture were studied. Chromatography separation of the thymic stromal cell supernatant showed that the cultured cells produced secretory substances generally detected in the molecular weight range of 1-13 kDa. Stimulation of the stromal cells in culture by freshly isolated syngeneic thymocytes increased concentration of the substances of the above molecular weight range.
Some biochemical and biological characteristics of supernatant from rat thymic stromal cell culture were studied. Chromatography separation of the thymic stromal cell supernatant showed that the cultured cells produced secretory substances generally detected in the molecular weight range of 1-13 kDa. Stimulation of the stromal cells in culture by freshly isolated syngeneic thymocytes increased concentration of the substances of the above molecular weight range.
