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[Antiphospholipid antibodies in acute coronary syndrome]
Pál Soltész1, Katalin Veres, Gabriella Lakos
1Debreceni Egyetem Orvos- és Egészségtudományi Centrum Altalános Orvostudományi Kar, III. sz. Belgyógyászati Klinika. soltesz@iiibel.dote.hu
Unlabelled:
The authors examined the presence of antiphospholipid antibodies in acute coronary syndrome. As their results show the frequency of antibodies against B2-glycoprotein I is significantly higher (14.4%) than the presence of these antibodies in a healthy control group (2%). Occurrence of antibodies against B2-glycoprotein I is much more higher than the occurrence of IgG- or IgM type antibodies against cardiolipin or lupus anticoagulant.
Conclusions:
The authors emphasize the possible role of anti-B2-glycoprotein I antibodies in thrombotic process of acute coronary syndrome. The previous ischaemic stroke was significantly more frequent in those patients medical history in whose serums antibodies against B2-glycoprotein I were present, so the presence of this thrombophil factor in acute coronary syndrome points out the importance of secunder antithrombotic prevention.