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DNA degradation and protein peroxidation in cells exposed to hydroxyl free radicals
1Department of Biological Sciences, Macquarie University, Sydney, New South Wales, Australia.
Redox Report : Communications in Free Radical Research
|April 12, 2003
Abstract:
The kinetics of DNA and protein damage in two lines of cultured cells exposed to radiation-generated hydroxyl free radicals were measured. The results show that DNA damage is a relatively late event, preceded by the formation of protein hydroperoxides which may play a role in the degradation of the DNA.