Functional assay systems for drug discovery at G-protein coupled receptors and ion channels

The Neural Cell Adhesion Molecule-Derived (NCAM)-Peptide FG Loop (FGL) Mobilizes Endogenous Neural Stem Cells and Promotes Endogenous Regenerative Capacity after Stroke.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology·2016

The synthetic NCAM mimetic peptide FGL mobilizes neural stem cells in vitro and in vivo.

Stem cell reviews and reports·2014

High-throughput screening and structure-based approaches to hit discovery: is there a clear winner?

Expert opinion on drug discovery·2013

The industrialisation of cellular screening.

Expert opinion on drug discovery·2013

The effect of tissue elastic properties and surfactant on alveolar stability.

Journal of applied physiology (Bethesda, Md. : 1985)·2010

Use of primary human cells in high-throughput screens.

Methods in molecular biology (Clifton, N.J.)·2009

Human gastric tissues simultaneously express the classical and alternative splicing cholecystokinin-B/gastrin receptors.

Receptors & channels·2005

Regulation of receptor-coupling to (multiple) G proteins. A challenge for basic research and drug discovery.

Receptors & channels·2005

High efficiency activation of L-type Ca2+ current by 5-HT in human atrial myocytes.

Receptors & channels·2005

Effects of losartan on blood pressure, oxidative stress, and nitrate/nitrite levels in the nitric oxide deficient hypertensive rats.

Receptors & channels·2005

Modification by L-NAME of codeine induced analgesia: possible role of nitric oxide.

Receptors & channels·2005

Inactivation-deficient human skeletal muscle Na+ channels (hNav1.4-L443C/A444W) in stably transfected HEK-293 cells.

Receptors & channels·2004

Distinct polyamine effects on Candida albicans morphogenesis identify spermidine as a key regulator.

Microbiology spectrum·2026

Immunogenicity of locally acting large molecule products: An overview.

Journal of clinical pharmacology·2026

Drug-drug interactions of NOACs with comedication: Prevalence and implications for adverse events in patients with atrial fibrillation.

Heart rhythm O2·2026

Antiplasmodial Activity and Safety Evaluation of Three Widely Distributed Polyherbal Antimalarials in Ghana.

Journal of tropical medicine·2026

Polygonatum odoratum (Mill.) Druce: A Review of Traditional Uses, Phytochemistry, Mass Spectrometric Fragmentation, Pharmacology, Toxicology, and Q-Marker Prediction.

Drug design, development and therapy·2026

Chemical basis for arginine citrullination by human PAD4.

Chemical communications (Cambridge, England)·2026

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Functional assay systems for drug discovery at G-protein coupled receptors and ion channels

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The Neural Cell Adhesion Molecule-Derived (NCAM)-Peptide FG Loop (FGL) Mobilizes Endogenous Neural Stem Cells and Promotes Endogenous Regenerative Capacity after Stroke.

The synthetic NCAM mimetic peptide FGL mobilizes neural stem cells in vitro and in vivo.

High-throughput screening and structure-based approaches to hit discovery: is there a clear winner?

The industrialisation of cellular screening.

The effect of tissue elastic properties and surfactant on alveolar stability.

Use of primary human cells in high-throughput screens.

Human gastric tissues simultaneously express the classical and alternative splicing cholecystokinin-B/gastrin receptors.

Regulation of receptor-coupling to (multiple) G proteins. A challenge for basic research and drug discovery.

High efficiency activation of L-type Ca2+ current by 5-HT in human atrial myocytes.

Effects of losartan on blood pressure, oxidative stress, and nitrate/nitrite levels in the nitric oxide deficient hypertensive rats.

Modification by L-NAME of codeine induced analgesia: possible role of nitric oxide.

Inactivation-deficient human skeletal muscle Na+ channels (hNav1.4-L443C/A444W) in stably transfected HEK-293 cells.

Distinct polyamine effects on Candida albicans morphogenesis identify spermidine as a key regulator.

Immunogenicity of locally acting large molecule products: An overview.

Drug-drug interactions of NOACs with comedication: Prevalence and implications for adverse events in patients with atrial fibrillation.

Antiplasmodial Activity and Safety Evaluation of Three Widely Distributed Polyherbal Antimalarials in Ghana.

Polygonatum odoratum (Mill.) Druce: A Review of Traditional Uses, Phytochemistry, Mass Spectrometric Fragmentation, Pharmacology, Toxicology, and Q-Marker Prediction.

Chemical basis for arginine citrullination by human PAD4.

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Functional assay systems for drug discovery at G-protein coupled receptors and ion channels

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