Related Experiment Video

Updated: Sep 26, 2026

A Catheter-Related Candida albicans Infection Model in Mouse
03:24

A Catheter-Related Candida albicans Infection Model in Mouse

Published on: March 22, 2024

[Invasive candidosis in intensive care unit patients]

A Glöckner1

  • 1Neurologisches Rehabilitationszentrum Greifswald, Karl-Liebknecht-Ring 26A, D-17491 Greifswald, Deutschland. a.gloeckner@nrz-greifswald.de

Mycoses
|April 15, 2003
PubMed

Insights

Invasive candidosis is rising globally with high mortality. Identifying risk factors is crucial for effective antifungal treatment in intensive care units, where current diagnostics and therapies face challenges.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Critical Care Medicine

Context:

  • Rising global incidence of invasive candidosis.
  • High mortality rates associated with invasive fungal infections.
  • Challenges in diagnosing and treating invasive candidosis in intensive care units (ICUs).

Purpose:

  • To highlight the importance of identifying risk factors for invasive candidosis.
  • To address the difficulties in diagnostic evaluation and antifungal treatment indications in ICUs.
  • To discuss limitations of current antifungal therapies and the potential of new agents.

Summary:

  • Invasive candidosis is an increasing worldwide threat with significant mortality.
  • Accurate diagnosis and appropriate antifungal treatment in ICUs remain challenging.
  • Development of new antifungals is essential to overcome limitations of existing therapies.

Impact:

  • Improved understanding of risk factors may lead to earlier detection and intervention.
  • Advances in diagnostics and treatment strategies could reduce mortality from invasive candidosis.
  • New antifungal agents promise enhanced efficacy and safety profiles for patient care.

More Related Videos

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract07:42

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

Candida albicans Biofilm Development on Medically-relevant Foreign Bodies in a Mouse Subcutaneous Model Followed by Bioluminescence Imaging08:31

Candida albicans Biofilm Development on Medically-relevant Foreign Bodies in a Mouse Subcutaneous Model Followed by Bioluminescence Imaging

Published on: January 27, 2015

Related Concept Videos

Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...