Related Experiment Video
Updated: Sep 26, 2026

Formulation and Characterization of Bioactive Agent Containing Nanodisks
Published on: March 17, 2023
[Amphotericin B and its lipid formulations]
1Klinik und Poliklinik für Kinderheilkunde, Pädiatrische Hämatologie/Onkologie, Albert-Schweitzer-Str. 33, 48149 Münster, Deutschland. ritterj@uni-muenster.de
Abstract:
More than 40 years after its approval, Amphotericin B is still the gold standard in the treatment of invasive fungal infections due to Candida and Aspergillus spp. Three different lipid formulations of Amphotericin B have been available for over 10 years, with only one of them, i.e. liposomal Amphotericin B (Ambisome), approved in Germany. Liposomal Amphotericin B is superior to conventional Amphotericin B due to its reduced nephrotoxicity, the option of a higher initial loading-dose, and fewer infusion-related side-effects, all this with identical or even higher efficacy.
More Related Videos
Related Concept Videos
Antifungal Agents
Antiprotozoal Agents
Cryptococcal Meningitis
Bioavailability Enhancement: Drug Permeability Enhancement
Candidiasis
Asymmetric Lipid Bilayer

