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Antipsychotic drug-induced movement disorders
1Department of Stomatology, Faculty of Dentistry, Universite de Montreal, Hôtel-Dieu du CHUM, Montreal, QC, Canada.
Summary
Diagnosing drug-induced movement disorders requires a high suspicion for offending medications, including past prescriptions and those from family. Antipsychotics and dopamine blockers are primary culprits, presenting acute and tardive motor complications.
Area of Science:
- Neurology
- Pharmacology
Background:
- Abnormal involuntary movement (AIM) disorders can stem from various medications.
- A high index of suspicion is crucial for early diagnosis of drug-induced movement disorders.
Purpose of the Study:
- To review the spectrum of drug-induced movement disorders.
- To highlight the central role of antipsychotics and dopamine receptor blockers.
Main Methods:
- Review of literature on drug-induced movement disorders.
- Focus on acute and tardive motor complications of antipsychotics.
- Brief coverage of other drug classes in table format.
Main Results:
- Antipsychotic drugs and dopamine receptor blockers are major causes of drug-induced movement disorders.
- These agents can lead to various acute and tardive motor complications.
- Other medications like antidepressants and lithium can also induce movement disorders.
Conclusions:
- Early identification of drug-induced movement disorders is vital.
- Thorough medication history, including past and potential exposures, is essential.
- Antipsychotics are key agents to consider in drug-induced movement disorders.