Comparison of three heart disease specific health-related quality of life instruments

N Oldridge1, A Perkins, Z Hodes

  • 1Indiana University Center for Aging Research School of Allied Health Sciences, Regenstrief Institute for Health Care, RG6, 1050 Wishard Boulevard, Indianapolis, IN 46202, USA. noldridg@iupui.edu

Insights

Specific health-related quality of life instruments are feasible for comparing outcomes in heart failure, angina, and myocardial infarction patients. These tools effectively differentiate patient groups, including those with anxiety or depression.

Area of Science:

  • Cardiology
  • Health Outcomes Research
  • Psychometrics

Background:

  • Assessing health-related quality of life (HRQL) in heart disease patients is crucial for outcome comparisons.
  • Existing HRQL instruments for heart failure, angina, and myocardial infarction (MI) may be applicable across diverse patient groups.

Purpose of the Study:

  • To evaluate the feasibility of using specific HRQL instruments for outcome comparisons in pure or mixed populations of patients with heart failure, angina, or MI.
  • To determine if existing HRQL tools can effectively differentiate patient outcomes across different cardiac diagnoses.

Main Methods:

  • A battery of specific HRQL questionnaires (Minnesota Living with Heart Failure, Seattle Angina Questionnaire, MacNew Heart Disease) and generic surveys (SF-36, Hospital Anxiety and Depression Scale) were administered.
  • 161 out of 205 patients (78.5%) with heart conditions returned the mailed questionnaires.

Main Results:

  • No significant differences in HRQL scales were found based on diagnostic category (heart failure, angina, MI).
  • Strong correlations existed between corresponding scales of specific HRQL instruments and between specific and generic SF-36 scales.
  • Patients experiencing anxiety or depression showed significant differences across most HRQL measures.

Conclusions:

  • A common HRQL instrument could be valuable for comparing outcomes in mixed populations of heart failure, angina, and MI patients.
  • Specific HRQL instruments demonstrate utility in assessing patient-reported outcomes across various heart disease diagnoses.
Abstract

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