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Effect of cardiac rehabilitation on lipid profile
N M Fard1, N S Zadegan, F Sajadi
1Isfahan Cardiovascular Research Centre, Isfahan, Iran.
Insights
Cardiac rehabilitation significantly improves serum lipid profiles in patients with heart conditions. This program, including exercise and consultations, helps normalize cholesterol and triglycerides, crucial for cardiovascular health.
Area of Science:
- Cardiology
- Preventive Medicine
- Clinical Research
Background:
- Hyperlipidemia is a significant risk factor for coronary heart disease.
- It is identified as the second major risk factor in Isfahan, Iran.
Purpose of the Study:
- To investigate the impact of a comprehensive cardiac rehabilitation program on serum lipid levels.
- To assess changes in total cholesterol, triglycerides, LDL-C, and HDL-C.
Main Methods:
- A randomized controlled trial involving 120 patients post-myocardial infarction or surgery.
- The intervention group (60 patients) underwent 24 exercise sessions with dietary and psychiatric support.
- The control group (60 patients) received standard care. Lipid profiles were measured pre- and post-intervention (8 weeks).
Main Results:
- The intervention group showed significant reductions in total cholesterol (T.chol), triglycerides (TG), and LDL-cholesterol (LDL-C).
- HDL-cholesterol (HDL-C) levels increased significantly in the intervention group.
- Improvements included a 20 mg/dl reduction in T.chol, 56 mg/dl in TG, 30 mg/dl in LDL-C, and a 5 mg/dl increase in HDL-C.
Conclusions:
- Cardiac rehabilitation effectively improves lipid profiles in cardiac patients.
- The program leads to normalization of lipid levels and reduces cardiovascular risk factors.
- Continuous participation in rehabilitation is recommended for sustained cardiac health benefits.
Background:
Hyperlipidemia plays a strong role in coronary heart disease and is the second major risk factor in Isfahan, Iran.
Objective:
To study the effect of cardiac rehabilitation on serum lipids.
Material And Methods:
The group of 120 patients. Suffering from myocardial infarction or undergone surgery divided into two groups of 60 each. Sixty patients participated in cardiac rehabilitation programme with 24 exercise sessions (45-60 min/session) with dietary and psychiatric consultation. Other group of 60 acted as control. The 14 hours footing blood samples were analysed pre-intervention and eight weeks post-intervension for total cholesterol (T.chol) triglycerides (TG), LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C).
Results:
T.chol, TG, LDL-C, and HDL-C was normal in 21 (35%), 18 (30%), 41 (68%) and 40 (66%) respectively after eight weeks in intervension group. T.chol, TG and LDL-C was decreased in 42 (70%), 36 (62%) and 46 (76%) of patient respectively in intervension group HDL-C showed increase in 52 (86%) patients. A 20 mg, 56 and 30 mg/dl reduction in T.chol, TG and LDL-C was noted after eight weeks intervention respectively. There was 0.8 reduction in LDL-C/HDL-C (P < 0.05) and 5 mg/dl increase in serum HDL-C (P < 0.05) of intervention group vs. control group.
Conclusions:
The decrease in T.chol, TG and LDL-C and increase in HDL-C in all patients and normalization of lipid profile in most of them shows the importance of rehabilitation in cardiac patients and the need for its continuity.