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Salivary gland tumours: immunoexpression of integrins beta 1, beta 3 and beta 4

S V L Loducca1, A Mantesso, S Kapas

  • 1Immunopathology Laboratory, Tropical Medicine Institute of the University of São Paulo, Brazil. sloducca@hotmail.com

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
|April 16, 2003
PubMed
Abstract

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Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
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