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Action of pyrethrum-based formulations against grain weevils
R Biebel1, E Rametzhofer, H Klapal
1Institute of Pharmaceutical Technology and Biopharmaceutics, Centre of Pharmacy, University of Vienna, Althanstrasse 14, A-1090, Vienna, Austria.
International Journal of Pharmaceutics
|April 16, 2003
Summary
Complexing pyrethrum extract with gamma-cyclodextrin enhances its insecticidal action against stored product pests. Piperonyl butoxide remains the most effective synergist for pyrethrum-based pesticides.
Area of Science:
- Agricultural Science
- Entomology
- Pest Management
Background:
- Pyrethrum extract is a natural pesticide effective against stored product pests.
- Low light stability limits pyrethrum's effectiveness in outdoor applications.
- Gamma-cyclodextrin complexation can improve pyrethrum's stability and efficacy.
Purpose of the Study:
- To evaluate the insecticidal activity of gamma-cyclodextrin complexed pyrethrum extract against the grain weevil.
- To assess the synergistic effects of piperonyl butoxide, sesamol, and tocopherol acetate on pyrethrum's efficacy.
- To determine optimal concentrations for pyrethrum and synergists in pest control formulations.
Main Methods:
- Complexation of pyrethrum extract with gamma-cyclodextrin.
- Testing insecticidal activity against grain weevils with various pyrethrum formulations and synergists.
- Comparing efficacy against a commercial pyrethrum product.
Main Results:
- Gamma-cyclodextrin complexation slightly enhanced pyrethrum's insecticidal action compared to free pyrethrum.
- Piperonyl butoxide demonstrated significant synergistic activity.
- Natural synergists sesamol and tocopherol acetate showed minor synergistic effects, even at higher concentrations.
Conclusions:
- Complexation with gamma-cyclodextrin offers a viable strategy to improve pyrethrum's stability and insecticidal performance.
- Piperonyl butoxide is a highly effective synergist for pyrethrum-based insecticides.
- Optimal formulation involves 0.3% pyrethrum extract and 3% piperonyl butoxide for grain weevil control.