Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lithium effects upon components of activity in rats.

F N Johnson

    Experientia
    |February 15, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Lithium chloride administration to rats altered activity levels, including reduced ambulatory and rearing behaviors. Some behavioral changes were sex-specific, suggesting subtle lithium effects on animal behavior.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The evolution of lithium therapy.

    Journal of psychopharmacology (Oxford, England)·2012
    Same author

    The long term prophylaxis of affective disorders.

    Advances in biochemical psychopharmacology·1995
    Same author

    [Lithium and sensory analysis].

    L'Encephale·1989
    Same author

    Different treatment modalities for recurrent bipolar affective disorders: an integrative approach.

    Psychotherapy and psychosomatics·1986
    Same author

    Psychoactive drugs and stimulus analysis: IV. The experimental discrimination of acute and prophylactic antidepressants.

    The International journal of neuroscience·1983
    Same author

    Psychoactive drugs and stimulus analysis: VI. Evaluation of one-trial modification of exploration as a basis for psychoactive drug classification.

    The International journal of neuroscience·1983
    Same journal

    On the influence of aneurine on the formation of nitrogenic bacterial nodites.

    Experientia·2010
    Same journal

    Around the biochemical activities of the flavobacterium.

    Experientia·2010
    Same journal

    Electron microscopic investigations on cellulose fibers after treatment with ultrasound.

    Experientia·2010
    Same journal

    Reviving scientific life in Hungary.

    Experientia·2010
    Same journal

    A new method for the production of deoxy sugars.

    Experientia·2010
    Same journal

    About the aneine content of the irritated and irritated frog nerves after poisoning with mono-iodoacetic acid.

    Experientia·2010
    See all related articles

    Area of Science:

    • Neuroscience
    • Pharmacology
    • Animal Behavior

    Background:

    • Lithium is a mood-stabilizing drug with known neurological effects.
    • Previous research has indicated lithium's impact on various behavioral components.

    Purpose of the Study:

    • To investigate the specific behavioral changes induced by lithium chloride administration in rats.
    • To explore potential sex-related differences in lithium's behavioral effects.

    Main Methods:

    • Rats were administered lithium chloride.
    • Multiple components of animal activity were monitored and analyzed.
    • Behavioral changes, including ambulatory, rearing, and oro-facial activities, were assessed.

    Main Results:

    Related Experiment Videos

  • Lithium chloride administration resulted in decreased ambulatory and rearing activity in rats.
  • Specific behaviors involving the mouth and nose were also reduced.
  • Observed behavioral modifications exhibited sex-related variations.

    • Conclusions:

    • Lithium chloride significantly alters rat behavior, impacting general activity and specific oro-facial actions.
    • The sex-specific nature of these changes suggests a nuanced mechanism of lithium's neurobehavioral influence.
    • Findings support the hypothesis that lithium's behavioral effects may be more subtle than previously understood.