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Leptomeningeal metastases.

Bonita M Gordon1, Jamie S Myers

  • 1bmgordon@healthmidwest.org

Clinical Journal of Oncology Nursing
|April 17, 2003
PubMed
Summary

Leptomeningeal metastases, a rare cancer complication, are increasing in breast and lung cancers due to better treatments. This condition affects the central nervous system, requiring specialized nursing care and offering poor prognoses.

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Area of Science:

  • Oncology
  • Neurology
  • Cancer Research

Background:

  • Leptomeningeal metastases (LM) are an increasing complication of systemic cancers, particularly breast and lung cancer.
  • Improved cancer treatments lead to longer survival, increasing the incidence of LM.

Observation:

  • LM presents with diverse central nervous system symptoms affecting the brain, cranial nerves, and spinal nerve roots.
  • Diagnosis relies on MRI with contrast and cerebrospinal fluid pathology.
  • Treatment often combines radiation and intrathecal chemotherapy.

Findings:

  • Outcomes for leptomeningeal metastases remain poor, with a short survival period of six weeks to six months.
  • Nurses are crucial in managing LM patients, monitoring neurological function, and administering treatments.

Implications:

  • Effective nursing care is vital for patients with leptomeningeal metastases, encompassing symptom management, chemotherapy administration, and psychosocial support.
  • Further research into improved therapeutic strategies and supportive care for LM is warranted.

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