The mouse (Mus musculus) T cell receptor alpha (TRA) and delta (TRD) variable genes

¹IMGT, Laboratoire d'ImmunoGénétique Moléculaire (LIGM), Université Montpellier II, Institut de Génétique Humaine, UPR CNRS 1142, 141 rue de la Cardonille, 34396 5, Montpellier Cedex, France.

Developmental and Comparative Immunology

|April 17, 2003

Abstract:

'The Mouse (Mus musculus) T cell receptor alpha (TRA) and delta (TRD) variable genes' 'IMGT Locus in Focus' report provides the first complete list of the mouse TRAV and TRDV genes which span 1550 kb on chromosome 14 at 19.7 cM. The total number of TRAV genes per haploid genome is 98 belonging to 23 subgroups. This includes 10 TRAV/DV genes which belong to seven subgroups. The functional TRAV genomic repertoire comprises 72-82 TRAV (including 9-10 TRAV/DV) belonging to 19 subgroups. The total number of TRDV genes per haploid genome is 16 (including the 10 TRAV/DV) belonging to 12 subgroups. The functional TRDV genomic repertoire comprises 14-15 genes (5 TRDV and 9-10 TRAV/DV) belonging to 11-12 subgroups. The eight tables and three figures of this report are available at the IMGT Marie-Paule page of IMGT. The international ImMunoGeneTics information system (http://imgt.cines.fr) created by Marie-Paule Lefranc, Université Montpellier II, CNRS, France.

Related Experiment Videos

The mouse (Mus musculus) T cell receptor alpha (TRA) and delta (TRD) variable genes

Related Concept Videos

IMGT Nomenclature and IMGT Unique Numbering: The Two Pillars of 35 Years of Immunoinformatics for Immunoglobulins (IG) or Antibodies and T Cell Receptors (TR).

IMGT® Nomenclature of Immunoglobulins (IG) or Antibodies and T Cell Receptors (TR): A Common Language for Immunoinformatics and Artificial Intelligence (AI).

Identification of engineered IMGT Fc variants in IMGT/mAb-DB, a database of therapeutic antibodies and fusion proteins.

Three-Dimensional Modeling of Camelus dromedarius T Cell Receptor Gamma (TRG)_Delta (TRD)/CD1D Complex Reveals Different Binding Interactions Depending on the TRD CDR3 Length.

Using IMGT unique numbering for IG allotypes and Fc-engineered variants of effector properties and half-life of therapeutic antibodies.

Evolution of T cell receptor beta loci in salmonids.

Efficacy of a composite aluminum adjuvant containing inulin in protecting turbot (Scophthalmus maximus) against Aeromonas salmonicida infection.

The ascidian phagocyte: a multitasking cell.

Characterization and immunomodulatory profiling of C-reactive protein and serum amyloid P component from spotted sea bass (Lateolabrax maculatus).

Identification and analysis of lncRNA50877, which is involved in KRT8-mediated mitochondrial homeostasis and GCRV replication in grass carp (Ctenopharyngodon idella).

Pathogen Recognition and Anti-infective Immune Responses Mediated by TLR22 in largemouth bass Micropterus salmoides.

Identification of ATG genes in the noble scallop Chlamys nobilis reveals unique expression strategies against low-temperature and Vibrio parahaemolyticus challenge.

Binding specificity of IgG antibodies to mycobacterial DNA in plasmas of patients with tuberculosis and healthy controls.

Age-related changes in the human T cell receptor alpha repertoire suggest positive selection of dual-specific T cells.

Clinical and endoscopic features of checkpoint inhibitor-induced colitis and their association with selective immunosuppressive therapy use.

Vaccine Ligand Binding Assay Development.

Immunohistochemistry Assay Based on Ready-To-Use Antibodies and Vendor-Recommended Protocol Settings Often Perform Suboptimally.

Gene-edited hypoimmune islets as a cure for type 1 diabetes: a review of the immunological challenges.

Related Experiment Videos

The mouse (Mus musculus) T cell receptor alpha (TRA) and delta (TRD) variable genes

Abstract:

Related Concept Videos

Related Articles