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Published on: May 21, 2019
Detection of cerebral hypoperfusion with bispectral index during paediatric cardiac surgery
M Hayashida1, M Chinzei, K Komatsu
1Department of Anaesthesiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Japan. hayashida-todai@umin.ac.jp
Background:
The bispectral index (BIS) may indicate changes in cerebral activity when the cerebral circulation is affected by acute hypotension.
Methods:
We measured BIS and cerebral haemoglobin saturation (Sr(O(2))) by near-infrared spectroscopy in 10 children undergoing cardiac surgery.
Results:
We noted 14 episodes of simultaneous decreases in Sr(O(2)) and BIS during acute hypotension in five children. An acute decrease in BIS, which coincided with a decrease in Sr(O(2)) suggesting a reduction in cerebral blood flow, was associated with acute slowing of the raw EEG waveforms.
Conclusions:
Our findings suggest that an acute decrease in BIS during acute hypotension indicates cerebral hypoperfusion, and that cerebral hypoperfusion caused by hypotension may occur frequently during paediatric cardiac surgery.

