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Predetermination of ovulation timing by luteinizing hormone assay
Fertility and Sterility
|April 1, 1976
Summary
A new rapid radioimmunoassay accurately predicts ovulation time. This simplified method aids in managing infertility by providing timely results.
Area of Science:
- Endocrinology
- Reproductive Medicine
- Assay Development
Background:
- Accurate prediction of ovulation is crucial for infertility management.
- Existing methods for ovulation prediction can be time-consuming or complex.
Purpose of the Study:
- To present a modified, rapid solid-phase radioimmunoassay for serum luteinizing hormone (LH).
- To evaluate the utility of this assay in predetermining ovulation time for infertile patients.
Main Methods:
- Development of a modified solid-phase radioimmunoassay.
- Shortened incubation time to 1 1/2 hours.
- Application of the assay in six infertile patients to determine ovulation timing.
Main Results:
- The assay demonstrated a reduced incubation time, enhancing efficiency.
- Successful predetermination of ovulation time in all six patients studied.
- The method proved to be simple and accurate.
Conclusions:
- The modified radioimmunoassay is a practical tool for LH measurement.
- This rapid assay can significantly aid in the clinical management of infertility.
- The simplicity and accuracy support its use in reproductive endocrinology practices.