Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Glaucoma-filtering bleb infections.

Ivan Mac1, Joern B Soltau

  • 1Department of Opthalmology, University of Louisville School of Medicine, Louisville, Kentucky, USA.

Current Opinion in Ophthalmology
|April 17, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of Cumulative Incidence and Severity of Primary Open-Angle Glaucoma Among Participants in the Ocular Hypertension Treatment Study After 20 Years of Follow-up.

JAMA ophthalmology·2021
Same author

Immunoproteomic analysis of potential serum biomarker candidates in human glaucoma.

Investigative ophthalmology & visual science·2012
Same author

Topical ocular hypotensive medication and lens opacification: evidence from the ocular hypertension treatment study.

American journal of ophthalmology·2006
Same author

Changing paradigms in the medical treatment of glaucoma.

Survey of ophthalmology·2002

Glaucoma-filtering bleb infections are increasing, particularly late-onset infections after using antifibrotic agents during surgery. Vigilant and aggressive management is crucial to prevent vision loss from these serious complications.

Area of Science:

  • Ophthalmology
  • Surgical Complications
  • Infectious Diseases

Background:

  • Glaucoma surgery, particularly trabeculectomy with antifibrotic agents (mitomycin, fluorouracil), is associated with an increased incidence of filtering bleb infections.
  • These infections can range from localized blebitis to severe endophthalmitis, posing a significant risk to vision.

Purpose of the Study:

  • To review the current literature on the management of glaucoma-filtering bleb infections.
  • To identify risk factors and optimal treatment strategies for these sight-threatening complications.

Main Methods:

  • Literature review of studies on glaucoma-filtering bleb infections.
  • Analysis of reported incidence, risk factors, and treatment outcomes.

Main Results:

Related Experiment Videos

  • Increased incidence of late-onset bleb infections is linked to antifibrotic use in trabeculectomy.
  • Identified risk factors include bleb location, bleb height, blepharitis, late bleb leaks, antifibrotic agents, chronic antibiotic use, and trabeculectomy alone.
  • Infections range from blebitis to endophthalmitis.

Conclusions:

  • Optimal treatment for bleb infections is evolving, emphasizing vigilance and aggressive management.
  • Glaucoma procedures achieving the lowest intraocular pressure may increase the risk of bleb-related infections.
  • Prompt and thorough treatment is essential to prevent vision loss.