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Updated: Sep 26, 2026

Simultaneous Electrocardiography Recording and Invasive Blood Pressure Measurement in Rats
Published on: January 31, 2019
The clinical relevance of systolic pressure variations in anesthetized nonhypotensive patients
Nicolas Dalibon1, Thierry Guenoun, Didier Journois
1Service d'Anesthésie, Hôpital Foch, Suresnes, France.
Objective:
To assess the accuracy of respiratory-induced systolic pressure variation and its components to detect low left ventricular preload.
Design:
Prospective study.
Setting:
University hospital.
Participants:
Sixty-seven patients undergoing major surgery under general anesthesia.
Interventions:
Transesophageal echocardiographic measurements during apnea and mechanical ventilation.
Measurements And Main Results:
Respiratory-induced systolic pressure variation and its components and left ventricular end-diastolic area obtained by transesophageal echocardiography were noted simultaneously. Arterial pressure indices did not allow a reliable diagnosis of a low left ventricular end-diastolic area using a cut-off value of 7.9 cm(2)/m(2) (inferior boundary of the interquartile range of the areas measured in the authors' group).
Conclusions:
These results suggest that systolic pressure variations noticed after induction of general anesthesia do not reflect low left ventricular preload in nonhypotensive patients.
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