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Updated: Sep 26, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
[Predictors of life-threatening arrhythmias in patients with implanted cardioverters-defibrillators]
Insights
Life-threatening cardiac arrhythmia in patients with implantable cardioverter-defibrillators (CD) is influenced by heart failure, prior induced ventricular tachycardia, and myocardial infarction history. Identifying high-risk patients can improve ICD therapy and patient quality of life.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Device Technology
Context:
- Implantable cardioverter-defibrillators (ICDs) are crucial for managing life-threatening cardiac arrhythmias.
- Predicting ICD discharge frequency and onset of arrhythmias is vital for patient management.
- Understanding risk factors is key to optimizing ICD therapy and patient outcomes.
Purpose:
- To identify and analyze factors influencing the onset and frequency of life-threatening cardiac arrhythmias in patients with ICDs.
- To determine specific patient characteristics associated with increased arrhythmia events.
- To stratify patients into high-risk groups for proactive management.
Summary:
- A study of 149 patients with ICDs examined 70 characteristics to identify arrhythmia predictors.
- Key factors identified include NYHA class III-IV heart failure, induced ventricular tachycardia, myocardial infarction (MI) history (especially multiple MIs), and supraventricular tachycardia.
- These findings enable the selection of high-risk patient groups.
Impact:
- Provides data for developing recommendations to reduce ventricular tachyarrhythmia and ICD discharges.
- Aims to enhance the quality of life for patients with ICDs.
- Can inform and refine indications for ICD implantation, ensuring appropriate patient selection.
Abstract:
To determine and analyze factors influencing onset of life-threatening cardiac arrhythmia in patients with implanted cardioverters-defibrillators (CD), 149 patients were examined by 70 characteristics including results of medical examination prior to implantation of CD, data of regular postoperative outpatient control. It was found that onset and discharge frequency of CD depended much on cardiac failure of NYHA functional class III-IV (p = 0.0423), induced ventricular tachycardia in electrophysiological test (p = 0.029), myocardial infarction (MI) without operative revascularization (p = 0.042) or 2 and more MIs irrespective of revascularization (p = 0.002), supraventricular tachycardia (p = 0.041). Groups of high risk to develop life-threatening arrhythmia among patients with implanted CD were selected. The results of the investigation can be used for the design of recommendations how to reduce the probability of ventricular tachyarrhythmia and how to lessen the frequency of CD operation and raise quality of life for patients with implanted CD. Moreover, the findings can be used for specifying indications for CD implantation.
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