[Homotransplantation of the spleen]

A report of experiences and results on 63 homotransplantations of spleen in dogs is given; 50 of the transplantations were performed in an orthotopic and 13 in a heterotopic way. 10 of the latter had undergone an earlier splenectomy and 3 an earlier orthotopic transplantation, followed by a complete resorption of the first transplant. The course of the transplant was observed by scintigraphy, the function of the anastomosis was controlled by angiography. The immunological and hematological changes were analyzed together with the changes of the protein-electrophoresis and those of the fibrinogenic factors. Scintigraphy has proved to be very useful for the diagnosis of transplant rejection; the measurement of the activity of the lysozyme in the serum compared with the pathoanatomical findings showed a characteristic increase of the activity of the lysozyme during the rejection crisis.