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False-positive technetium 99m depreotide scintigraphy resulting from round atelectasis
Linda P Thomas1, Antonio G Balingit, David S Morison
1Department of Radiology, Madigan Army Medical Center, Tacoma, WA 98431, USA. lindathomasp@yahoo.com
Journal of Thoracic Imaging
|April 18, 2003
Summary
Round atelectasis can mimic malignancy on imaging scans. Increased technetium (Tc) 99m depreotide uptake in round atelectasis suggests it is a potential nonmalignant cause of positive scintigraphy results.
Area of Science:
- Radiology
- Nuclear Medicine
- Oncology
Background:
- Diagnostic imaging plays a crucial role in differentiating benign from malignant thoracic conditions.
- Technetium (Tc) 99m depreotide scintigraphy is utilized in the evaluation of suspected malignancy.
Observation:
- Two cases of round atelectasis demonstrated unexpected increased accumulation of Tc 99m depreotide.
- Imaging modalities included planar scintigraphy and single-photon emission computed tomographic (SPECT) imaging.
Findings:
- Round atelectasis exhibited significant radiotracer uptake on Tc 99m depreotide scintigraphy.
- This uptake pattern mimicked findings typically associated with malignant neoplasms.
Implications:
- Round atelectasis should be considered in the differential diagnosis of positive Tc 99m depreotide scintigraphy.
- This finding may help avoid unnecessary invasive procedures for potentially benign conditions.