Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Genetic programs in development of three-dimensional organs].

Ryuichi Nishinakamura1

  • 1Division of Stem Cell Regulation, Institute of Medical Science, University of Tokyo.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|April 19, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The unconventional kinesin Kif26a is required for the guidance of major axon tracts in the developing mouse brain.

bioRxiv : the preprint server for biology·2026
Same author

Protective role of early Tnfsf15 upregulation in limiting glomerular injury and proteinuria in experimental Alport Syndrome.

Journal of pharmacological sciences·2026
Same author

Genetically Engineered Human iPS Cell-Derived Kidney Organoid Recapitulates an Early Stage of ALK Fusion Gene-Associated Renal Tumorigenesis.

Molecular cancer research : MCR·2025
Same author

Selective modification of glycoprotein substrates by GnT-V in mouse kidney.

iScience·2025
Same author

Establishing a nanoluciferase-based assay as a high-throughput screening platform for therapeutics in congenital nephrotic syndrome.

Journal of pharmacological sciences·2025
Same author

Genetic knockout suggests Isl1 enhancer redundancy in mouse hindlimb development.

Developmental biology·2025

Regenerative medicine uses stem cells for therapies. Mimicking embryonic development is key to creating functional three-dimensional organs in vitro for future medical breakthroughs.

Area of Science:

  • Regenerative medicine
  • Developmental biology
  • Stem cell research

Context:

  • Human embryonic stem cells (hESCs) established in 1998 spurred regenerative medicine.
  • Somatic stem cells offer potential for cell-based therapies.
  • Balancing clinical applications with developmental biology is crucial for long-term success.

Purpose:

  • To review the formation of three-dimensional (3D) organs.
  • To explore how developmental biology principles can be applied to organ generation.
  • To highlight the potential of in vitro organogenesis.

Summary:

  • This review examines the process of three-dimensional organ formation.
  • It discusses the role of stem cells, including human embryonic stem cells and somatic stem cells, in regenerative medicine.

Related Experiment Videos

  • The importance of understanding embryonic development for generating functional organs in vitro is emphasized.

    • Impact:

    • Provides insights into generating functional organs for transplantation.
    • Facilitates advancements in regenerative medicine and cell therapy.
    • Offers a framework for future research in developmental biology and tissue engineering.