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Allergic contact dermatitis to low molecular weight allergens in the chicken

H C Maguire, R G Rank, W P Weidanz

    International Archives of Allergy and Applied Immunology
    |January 11, 1976
    PubMed

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    Allergic Reactions: Anaphylaxis

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    Type III hypersensitivity reactions occur when antigen–antibody complexes form and activate the complement system. Normally, these complexes help the clearance of antigens by phagocytes and red blood cells. However, when large numbers of immune complexes are present, they can deposit in tissues—particularly in the walls of blood vessels—leading to inflammation and tissue injury. These deposits trigger complement activation and neutrophil recruitment, resulting in serum sickness, a systemic...