Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hepatitis E virus epidemiology in industrialized countries.

Pilar Clemente-Casares1, Sonia Pina, Maria Buti

  • 1University of Barcelona, Barcelona, Spain.

Emerging Infectious Diseases
|April 19, 2003
PubMed
Summary

Hepatitis E virus (HEV) is more common in industrialized nations than previously thought, with widespread circulation detected in sewage and potential swine reservoirs. This study highlights the simultaneous presence of diverse HEV strains in affected regions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dysregulation of Mast Cell Prostaglandin in Food Anaphylaxis.

Journal of investigational allergology & clinical immunology·2026
Same author

Caution in interpreting MRGPRX2 N62S as a disease-driving variant in chronic spontaneous urticaria.

The Journal of allergy and clinical immunology·2025
Same author

MITF regulates autophagy and extracellular vesicle cargo in gastrointestinal stromal tumors.

Molecular biomedicine·2025
Same author

Preclinical study of microphthalmia-associated transcription factor inhibitor ML329 in gastrointestinal stromal tumor growth.

Molecular therapy. Oncology·2025
Same author

Variants of the MRGPRX2 Gene Found in Patients With Hypersensitivity to Quinolones and Vancomycin Show Amplified and Drug-Specific Activation Responses In Vitro.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2025
Same author

Patient-reported outcomes in chronic hepatitis delta: An exploratory analysis of the phase III MYR301 trial of bulevirtide.

Journal of hepatology·2024

Area of Science:

  • Virology
  • Environmental Health
  • Public Health

Background:

  • Hepatitis E virus (HEV) is a significant public health concern globally.
  • Understanding HEV prevalence in industrialized nations is crucial for effective control strategies.

Purpose of the Study:

  • To assess the prevalence and diversity of Hepatitis E virus (HEV) in industrialized countries.
  • To investigate potential reservoirs and circulation patterns of HEV.

Main Methods:

  • Analysis of urban sewage samples from Spain, France, Greece, Sweden, and the United States for HEV detection.
  • Genotyping of identified HEV strains and comparison with existing isolates.
  • Investigation of pigs as a potential reservoir for HEV.

Main Results:

Related Experiment Videos

  • HEV was detected in 43.5% of urban sewage samples from Barcelona (1994-2002).
  • Fifteen HEV strains identified in Barcelona were similar to previous local isolates and strains from non-endemic areas.
  • HEV strains were also found in sewage from Washington D.C. and Nancy, France, alongside Hepatitis A virus.
  • A novel swine HEV strain was identified, suggesting pigs as a reservoir.

Conclusions:

  • HEV may be more prevalent in industrialized countries than previously recognized.
  • Multiple HEV strains can circulate concurrently within a single geographic region.
  • Pigs represent a potential reservoir for HEV, contributing to its circulation.