[Enteric infections in Perugia's area: laboratory diagnosis, clinical aspects and epidemiology during 2001]

Daniele Crotti1, Maria Letizia D'Annibale, Giovanna Fonzo

  • 1Sezione di Microbiologia e Parassitologia Clinica, A O di Perugia, P O R Silvestrini, Perugia, Italy.

Insights

This study analyzed 523 stool samples from patients with diarrhea, identifying common pathogens like rotavirus, Salmonella, and Campylobacter. Bacterial infections were more frequent in invasive enteritis cases.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Pediatrics

Context:

  • Analysis of 523 stool specimens from patients with recent diarrhea in 2001.
  • Inclusion of both pediatric (330) and adult (193) patient populations.
  • Comprehensive testing for a range of enteric pathogens including protozoa, rotavirus, adenovirus, Clostridium difficile toxin A, and common enteropathogenic bacteria.

Purpose:

  • To identify the prevalence of various enteric pathogens in patients presenting with diarrhea.
  • To investigate potential correlations between specific pathogens and clinical manifestations.
  • To determine seasonal patterns of infectious diarrhea and suggest diagnostic methodologies.

Summary:

  • Salmonella (12.8%), Campylobacter (9.9%), and Clostridium difficile toxin A (11.3%) were significant bacterial causes of diarrhea.
  • Rotavirus (41.4%) was the predominant viral pathogen, particularly in children aged 1-6 years.
  • While pathogens occurred year-round, bacterial infections peaked in spring/summer, and rotavirus in winter; invasive enteritis was exclusively bacterial.

Impact:

  • Highlights the etiological agents responsible for infectious diarrhea in the studied population.
  • Provides insights into seasonal variations of specific enteric infections.
  • Suggests a diagnostic approach for managing infectious diarrheal diseases effectively.

Related Concept Videos

Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...