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Updated: Aug 14, 2026
Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
Novel therapies for the treatment of non-small cell lung cancer
David H Johnson1, Joan H Schiller
1Division of Hematology and Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, 777 Preston Research Building, Nashville, TN 37232-6307, USA. david.johnson@mcmail.vanderbilt.edu
Abstract:
The management of advanced NSCLC remains a daunting challenge. However, new tools are available for treating this malignancy and continued progress is likely. The future is bright with a myriad of opportunities to exploit our ever-expanding knowledge of tumor biology. What is perhaps most needed, however, is development of new methods to prevent children and young adults from ever taking up the use of tobacco. In addition, we need new techniques to assist those who are already addicted to escape from tobacco's death grip. Sadly, most users of tobacco still fail to recognize the dangers of their habit. This needs to change!
Insights
Advanced non-small cell lung cancer (NSCLC) management is challenging. Future progress relies on understanding tumor biology and developing new tobacco cessation strategies to combat addiction and its dangers.
Area of Science:
- Oncology
- Public Health
Background:
- Advanced non-small cell lung cancer (NSCLC) presents significant treatment challenges.
- Despite progress, effective management of this malignancy remains a critical unmet need.
Purpose of the Study:
- To highlight advancements in NSCLC treatment strategies.
- To emphasize the urgent need for improved tobacco use prevention and cessation interventions.
Main Methods:
- Review of current therapeutic options for advanced NSCLC.
- Discussion on the role of tumor biology in treatment development.
- Analysis of public health strategies for tobacco control.
Main Results:
- Emerging tools and a deeper understanding of tumor biology offer promising avenues for NSCLC treatment.
- Significant gaps exist in preventing tobacco initiation and aiding cessation, particularly among young people.
Conclusions:
- Continued progress in NSCLC management is anticipated through biological insights.
- Addressing the tobacco epidemic through prevention and cessation is paramount for reducing cancer incidence and mortality.
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