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Tyzzer's disease in a dog.
Journal of the American Veterinary Medical Association
|April 1, 1976
Summary
A young dog presented with severe illness, showing signs of emaciation and gastrointestinal distress. Necropsy revealed concurrent infections with Bacillus piliformis and coccidia, contributing to liver and intestinal damage.
Area of Science:
- Veterinary Pathology
- Canine Infectious Diseases
Background:
- Investigating the etiology of severe gastrointestinal and hepatic disease in a young dog.
- Understanding the pathological manifestations of concurrent parasitic and bacterial infections in canines.
Observation:
- A 5-week-old mixed-breed dog exhibited profound emaciation, depression, anorexia, diarrhea, and vomiting.
- Subnormal rectal temperature and death on admission.
- Necropsy revealed focal hepatic lesions and catarrhal enteritis.
Findings:
- Microscopic examination showed coagulative necrosis in the liver with minimal inflammation.
- Organisms consistent with Bacillus piliformis identified in hepatocytes and intestinal mucosa.
- Coccidial forms found within intestinal epithelial cells, associated with focal necrosis.
Implications:
- This case highlights the potential for severe disease and mortality in young dogs due to concurrent Bacillus piliformis and coccidial infections.
- Emphasizes the importance of considering both protozoal and bacterial pathogens in diagnosing enteritis and hepatitis in dogs.
- Suggests that Bacillus piliformis (Tyzzer's disease) and coccidiosis can co-exist and contribute to a fatal outcome.