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The kinetic study of the selenium yeast stability
B Szulc1, F Ryszka, B Dolińska
1Department of Applied Pharmacy and Drug Technology, Silesian Medical Academy, Poland.
Abstract:
The kinetics of degradation of selenium yeast was investigated at different temperatures. The effect of temperature has been determined and from this data, applying of Arrhenius-law, the stability of selenium yeast at 25 degrees C has been predicted and the t10 was determined. The changes in selenium content of the selenium yeast were determined by the fluorimetric method. It was proved, that the decomposition observed the first-order kinetic equations. The shelf life of selenium yeast predicted from the Arrhenius plot exceeded 1126 days. In the other hand the stability of selenium preparation in normal storage conditions (T = 25 degrees C) was determined to compare with predicted values. These results were found in agreement with experimental ones obtained at room temperature. No discernible physical changes of selenium preparations were observed after the storage in normal conditions (25 degrees C).
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