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Effectiveness of pertussis vaccination in New South Wales, Australia, 1996-1998

Siranda Torvaldsen1, Judy M Simpson, Peter B McIntyre

  • 1National Centre for Immunisation Research and Surveillance, The Children's Hospital at Westmead, NSW, Australia. sirandat@chw.edu.au

European Journal of Epidemiology
|April 23, 2003
PubMed

Insights

Pertussis vaccination is highly effective in preventing whooping cough in children under 14 in New South Wales, Australia. Vaccine effectiveness (VE) was highest in younger children, highlighting the importance of immunization programs.

Area of Science:

  • Public Health
  • Epidemiology
  • Vaccinology

Background:

  • Pertussis (whooping cough) notifications have risen globally over the last decade.
  • This trend necessitates evaluating the effectiveness of existing pertussis vaccination strategies.

Purpose of the Study:

  • To estimate the vaccine effectiveness (VE) of the Australian whole-cell pertussis vaccine.
  • To assess VE in children under 14 years in New South Wales (NSW) between 1996 and 1998.

Main Methods:

  • Utilized notified pertussis cases and Australian Childhood Immunisation Register data.
  • Employed the screening method for VE calculation, adjusting for age, year of disease onset, and residence.
  • Analyzed data from children aged 8 months to 13 years.

Main Results:

  • Pertussis vaccination demonstrated high effectiveness in preventing notified cases.
  • VE was highest in the 8-23 month age group (91%) and lowest in the 9-13 year age group (78%).

Conclusions:

  • Pertussis vaccination is a highly effective public health intervention for preventing whooping cough in NSW children.
  • Continuous monitoring of VE is crucial, especially following the transition to acellular pertussis vaccines.

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