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Paraprotein and beta2-microglobulin analyses in multiple myeloma--do we need to monitor both?
David Sinclair1, Tanya Cranfield, Mary Ganczakowski
1Department of Chemical Pathology, Queen Alexandra Hospital, Portsmouth, UK. david.sinclair@porthosp.nhs.uk
Clinical Laboratory
|April 23, 2003
Abstract:
The relationship between serum paraprotein and beta2-microglobulin (B2m) levels was studied in serial samples from 41 patients with myeloma. A positive correlation coefficient was found in 70.7% of myeloma patients indicating that no extra information was gained from measuring both analytes routinely. As a result, the workload for B2m fell without any diminution in clinical service.