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Systemic 5-fluorouracil producing an inflammatory response in porokeratosis
W K Nahm1, K G Donohue, J F Danahy
1Boston University School of Medicine, Roger Williams Medical Center, Department of Dermatology and Skin Surgery, Providence, Rhode Island 02908, USA.
Abstract:
Topical 5-fluorouracil has been used as an effective treatment for porokeratosis. Upon its treatment, an inflammatory effect occurs with the topical 5-fluorouracil. We report a case of a patient with disseminated superficial actinic porokeratosis displaying a comparable inflammatory process following therapy with systemic 5-fluorouracil used to manage a metastatic breast cancer.