Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Immunity and survival.

C E Buckley, J M Roseman

Journal of the American Geriatrics Society

|June 1, 1976

Summary

This summary is machine-generated.

The immune system plays a key role in human longevity and survival. Researchers identified immune response (Ir) genes linked to infectious agents within families, suggesting a genetic component to immune function and lifespan.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Optimization of Cathode Functional Layers of Solid Oxide Electrolysis Cells.

ACS applied materials & interfaces·2020

Same author

Stabilization of volatile Ti(BH<sub>4</sub>)<sub>3</sub> by nano-confinement in a metal-organic framework.

Chemical science·2017

Same author

Complex transition metal hydrides: linear correlation of countercation electronegativity versus T-D bond lengths.

Chemical communications (Cambridge, England)·2015

Same author

Preparation, microstructure and hydrogen sorption properties of nanoporous carbon aerogels under ambient drying.

Nanotechnology·2011

Same author

KOH catalysed preparation of activated carbon aerogels for dye adsorption.

Journal of colloid and interface science·2011

Same author

Predictors of the rate of change in disease activity over time in LUMINA, a multiethnic US cohort of patients with systemic lupus erythematosus: LUMINA LXX.

Lupus·2010

Same journal

Caregiver Burden at the Onset of Acute Hospital-At-Home.

Journal of the American Geriatrics Society·2026

Same journal

Utilization Patterns Among Heterogeneous Subgroups of Homebound Older Adults: A Latent Class Analysis.

Journal of the American Geriatrics Society·2026

Same journal

Off-Label Initiation of Gabapentin and Valproic Acid Among Long-Stay Nursing Home Residents With and Without Dementia.

Journal of the American Geriatrics Society·2026

Same journal

The DOAC-FRAIL Study-Same Dose, Different Story: Prevalence of Deviant Direct Oral Anticoagulant Levels in Nursing Home Residents.

Journal of the American Geriatrics Society·2026

Same journal

Practice Environment and Job Outcomes Among Primary Care Nurse Practitioners Caring for Patients With Dementia.

Journal of the American Geriatrics Society·2026

Same journal

Anticholinergic Medication Use in Veterans Affairs Long-Term Care Residents: Clinical Patterns and Opportunities for Deprescribing.

Journal of the American Geriatrics Society·2026

See all related articles

Area of Science:

Immunology
Genetics
Gerontology

Background:

The immune system's role in aging and survival is increasingly recognized.
Genetic factors may influence immune responses and longevity.

Purpose of the Study:

To investigate the association between the immune system and human survival.
To identify genetic markers related to immune response in families.

Main Methods:

Analysis of immune system function in human family studies.
Examination of surviving older individuals.
Detection of immune response (Ir) genes.

Main Results:

Evidence suggests the immune system influences survival rates.

Immune response (Ir) genes associated with infectious agents were identified in human families.

Conclusions:

The immune system is a significant factor in controlling human longevity.
Genetic predisposition to immune response may impact lifespan and survival.