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Updated: Aug 20, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Outbreak of tuberculosis in a 2000-year-old Chinese population
Hisae Fusegawa1, Bing-Hua Wang, Kiyohiko Sakurai
1Department of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan.
Abstract:
The molecular identification of Mycobacterium tuberculosis DNA in ancient human remains has been achieved mainly in mummies with macroscopic changes but not in the skeletons without bone tuberculosis. Using polymerase chain reaction studies, we identified mycobacterial DNA in 2000-year-old human skeletons without pathological changes. Our findings suggest that these people suffered from an outbreak of tuberculosis. Molecular examinations for mycobacterial DNA in the bone marrow of skeletons may contribute to the clarification of ancient diseases in old human populations.
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