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Updated: Aug 12, 2026

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma
Published on: December 28, 2015
[Relapse of Hodgkin disease after 17 years of complete remission. A case report]
Guido Osorio1, Christian Caglevic
1Hospital de Enfermedades Infecciosas, Facultad de Medicina, Universidad de Chile. gosorios77@hotmail.com
Abstract:
A 45 years old male in whom a Hodgkin disease, nodular sclerosis variety, IIIBS, with splenectomy was diagnosed at the age of 27 years of age, is reported. He was treated initially with chemotherapy C-MOPP and radiotherapy, obtaining a complete remission of the disease two years later. In December 2000, after 17 years of remission, the disease relapsed with generalized lymph node enlargement and lung involvement. He was treated with ABVD chemotherapy, but died after 5 cycles due to a febrile neutropenia, bronchopneumonia and respiratory distress.

