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[Brachyurins--serine collagenolytic enzymes from crabs]
1Chemical Faculty, Moscow State University, Vorob'evy gory, GSP Moscow, 119899 Russia. laboratoriahps@hotmail.com
Bioorganicheskaia Khimiia
|April 24, 2003
Abstract:
The properties of brachyurins, proteolytic enzymes belonging to a new subfamily of chymotrypsin-like proteases, are considered. These enzymes, found in various species of crustacean, exhibit mixed substrate specificity and a marked collagenolytic activity. The enzymatic and physicochemical properties of brachyurins I and their primary and spatial structures are discussed in detail. A separate chapter is devoted to the preparations of collagenases from the hepatopancreas of king crab: their action on the damaged skin and use in medicine.