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Published on: December 19, 2010
Paecilomyces peritonitis: case report and review of the literature
K Wright1, S Popli, V C Gandhi
1Veterans Affairs Hospital, Hines, Illinois 60141, USA.
Abstract:
While filamentous fungi are a rare cause of peritonitis in peritoneal dialysis patients, there is increasing recognition of Paecilomyces species as pathogens in such patients. We herein report a case of fungal peritonitis secondary to the filamentous Paecilomyces variotii species. The patient had a long and ultimately fatal course of illness despite catheter removal, discontinuation of peritoneal dialysis, recurrent intraabdominal abscess drainage, and prolonged courses of antifungal therapy. Our experience with this case and a review of the literature suggests that infection with this fungus can cause substantial morbidity and is probably best treated with prompt catheter removal, aggressive antifungal therapy and vigilant observation for complications.
Insights
Filamentous fungi like Paecilomyces variotii rarely cause peritonitis in peritoneal dialysis patients. This case highlights the severe illness and challenges in treating such fungal infections, even with aggressive management.
Area of Science:
- Medical Mycology
- Infectious Diseases
Background:
- Peritonitis is a serious complication in patients undergoing peritoneal dialysis.
- Filamentous fungi are uncommon causes of peritonitis, but Paecilomyces species are increasingly recognized pathogens.
Observation:
- A case of fungal peritonitis caused by Paecilomyces variotii in a peritoneal dialysis patient is presented.
- The patient experienced a prolonged and fatal illness despite comprehensive treatment, including catheter removal and antifungal therapy.
Findings:
- Paecilomyces variotii can lead to severe morbidity in peritoneal dialysis-associated peritonitis.
- Treatment challenges include the need for aggressive antifungal therapy and prompt intervention.
Implications:
- Early diagnosis and prompt management, including catheter removal and aggressive antifungal treatment, are crucial for improving outcomes.
- Vigilant monitoring for complications is essential in managing Paecilomyces peritonitis.
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