Related Experiment Video

Updated: Aug 8, 2026

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
07:20

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Published on: December 21, 2012

Pseudomyxoma peritonei

R Harshen1, R Jyothirmayi, N Mithal

  • 1Epsom and St Helier NHS Trust, Epsom General Hospital, Epsom, Surrey, U.K.

Clinical Oncology (Royal College of Radiologists (Great Britain))
|April 24, 2003
PubMed

Insights

Pseudomyxoma peritonei, a rare mucinous ascites, likely originates from the appendix. Diagnosis involves imaging, but treatment, primarily surgery, remains controversial with chemotherapy

Area of Science:

  • Gastroenterology
  • Oncology
  • Pathology

Background:

  • Pseudomyxoma peritonei is a rare condition characterized by mucinous ascites and peritoneal/omental implants.
  • Its exact origin is debated, but appendiceal origin is increasingly supported by evidence.

Purpose of the Study:

  • To review the pathology, clinical features, and treatment options for pseudomyxoma peritonei.
  • To consolidate current understanding and highlight areas of controversy in managing this rare condition.

Main Methods:

  • Literature review of pathology, clinical presentation, and treatment modalities for pseudomyxoma peritonei.
  • Analysis of diagnostic imaging techniques (ultrasonography, CT, MRI) and therapeutic approaches.

Main Results:

  • Appendiceal origin is suggested by immunohistochemical and molecular genetic data.
  • Diagnosis is often incidental during laparotomy, with imaging aiding preoperative assessment.
  • Treatment primarily involves surgery, but its efficacy and the role of chemotherapy are not well-defined.

Conclusions:

  • Pseudomyxoma peritonei management requires further research, particularly regarding the role of chemotherapy.
  • Standardized diagnostic and treatment protocols are needed for this rare malignancy.

More Related Videos

Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens09:19

Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens

Published on: December 9, 2022

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms10:10

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms

Published on: April 17, 2026

Related Concept Videos

Peritoneum01:21

Peritoneum

The peritoneum is a vital membrane that lines the abdominal cavity and covers most of the organs within it. It plays a crucial role in protecting the organs, providing a smooth surface for their movement, and facilitating various physiological processes. Understanding the anatomy and function of the peritoneum is essential for comprehending the complexities of the abdominal region.
Anatomy of the Peritoneum
The peritoneum is divided into two layers: the parietal peritoneum and the visceral...
Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...