Related Experiment Videos
Intraperitoneal fluid accumulation induced by Clostridium perfringens alpha-toxin (phospholipase C)
Tsuneo Maegawa1, Xingmin Wang, Tadahiro Karasawa
1Department of Bacteriology, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-8640, Japan.
Acta Microbiologica Polonica
|April 24, 2003
Abstract:
We report that the intraperitoneal injection of Clostridium perfringens alpha-toxin into mice induces ascites. This phenomenon was monitored by measuring fluid volume and analyzing hematologic data. The mouse toxicity test provides a simple and useful model for examining C. perfringens alpha-toxin-induced vascular permeability.