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High prevalence of PER-1 extended-spectrum beta-lactamase-producing Acinetobacter spp. in Korea
Dongeun Yong1, Jong Hee Shin, Sinyoung Kim
1Department of Laboratory Medicine, Research Institute of Bacterial Resistance. BK21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Korea.
Antimicrobial Agents and Chemotherapy
|April 24, 2003
Abstract:
PER-1, an extended-spectrum beta-lactamase, has been reported only in Europe. We detected PER-1 in 53 of 97 acinetobacters in Korea, mainly in the sputum of intensive care unit patients. Pulsed-field gel electrophoresis analysis suggested that clonal spread had occurred. Only PCR reliably detected PER-1 producers. PER-1 producers may also exist in other Asian countries.