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Upper gastrointestinal cancer risk in familial adenomatous polyposis
T Jeffery Wieman1, Scott W Taber, Donald N Reed
1Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA.
The Journal of the Kentucky Medical Association
|April 25, 2003
Abstract:
Familial adenomatous polyposis has a known risk of colorectal carcinoma. Less well recognized, however, is the association with duodenal polyps and their subsequent malignant degeneration. While frequent endoscopic surveillance is acceptable, a case of early malignant transformation is presented, and the argument for prophylactic preemptive pancreaticoduodenectomy is made.